Biomarker discovery in low grade breast cancer: A proteomics based approach
| Název česky | Vyhledávání biomarkerů low-grade karcinomů prsu: Přístupy na bázi proteomiky |
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| Autoři | |
| Rok publikování | 2010 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Traditional prognostic markers of low-grade breast cancer are currently not sufficient for precise risk-group discrimination. Our effort was thus focused on biomarker discovery in this tumor group. Three proteomics approaches were involved in complex protein analysis of tissue lysates: SELDI-TOF MS, iTRAQ-2DLC-MS/MS and 2-D SDS-PAGE. Differentially expressed proteins belong to several functional groups related to breast cancer biology and are presented and discussed on the poster. |
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