3D Printed Polysaccharide-Based Capsules for Colon-Specific Drug Delivery
| Autoři | |
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| Rok publikování | 2025 |
| Druh | Konferenční abstrakty |
| Citace | |
| Popis | This research aims to investigate the feasibility of 3D printing a capsular device that utilizes a dual-trigger release mechanism. The capsule's primary structure would consist of HPMC, a polymer known for its time-dependent release properties. The addition of carefully selected natural polysaccharide (citrus pectin) would ensure degradation by colonic bacteria, providing a microbiota-triggered release component. 3D printing of capsules containing pectin has proven to be a suitable method for colonic drug delivery system manufacturing. The targeting of this colon drug delivery system was confirmed by in vivo release testing in healthy volunteers. |
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