Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials
| Autoři | |
|---|---|
| Rok publikování | 2020 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Engraftment of leukemic cells in immunodeficient mice can be improved by incorporation of a humanized bone marrow microenvironment, formed by mesenchymal stromal cells (MSC) and a suitable biomaterial. Various biomaterials ranging from ceramic calcium phosphate to extracellular matrix (ECM) gels were reported so far but their comparison is lacking. |
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