Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2018127
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
-
Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
-
Biotechnologický ústav AV ČR, v.v.i.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies, will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB is a part of the ESFRI project INSTRUCT-ERIC.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 322
2023
-
Editorial for the Special Issue: "Tick-Borne Encephalitis"
Microorganisms, rok: 2023, ročník: 11, vydání: 4, DOI
-
Efficacy and immunogenicity of a veterinary vaccine candidate against tick-borne encephalitis in dogs
Vaccine, rok: 2023, ročník: 41, vydání: 42, DOI
-
Efficient synthesis of novel 2′-deoxy-C-nucleosides containing oxa and thiadiazole derivatives and their biological activity.
Journal of Molecular Structure, rok: 2023, ročník: 1292, DOI
-
Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST – RE1-silencing transcription factor
Computational and Structural Biotechnology Journal, rok: 2023, ročník: 21, vydání: Dec, DOI
-
Ethanol Dehydrogenation over Copper-Silica Catalysts: From Sub-Nanometer Clusters to 15 nm Large Particles
ACS Sustainable Chemistry and Engineering, rok: 2023, ročník: 11, vydání: 30, DOI
-
Ethanol dehydrogenation to acetaldehyde with mesoporous Cu-SiO2 catalysts prepared by aerosol-assisted sol-gel
Chemical Engineering Journal, rok: 2023, ročník: 465, vydání: June, DOI
-
Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles
Journal of the American Society for Mass Spectrometry, rok: 2023, ročník: 34, vydání: 4, DOI
-
Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor
Nucleic Acids Research, rok: 2023, ročník: 51, vydání: 6, DOI
-
Hydrophobicity Boosts Catalytic Activity: The Tailoring of Aluminosilicates with Trimethylsilyl Groups
ChemCatChem, rok: 2023, ročník: 15, vydání: 13, DOI
-
Characterisation of invisible conformation of domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis
Rok: 2023, druh: Konferenční abstrakty