Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats
| Autoři | |
|---|---|
| Rok publikování | 2003 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | European Neuropsychopharmacology |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | 5-HT1 and 5-HT2 receptor ligands; methamphetamine; self-administration;rats |
| Popis | Present work brings new aspects into the understanding of methamphetamine addiction studying the role of two different serotonergic receptor subtypes 5-HT1 and 5-HT2. According to our results, the most important inhibitory influence for the conditioned reward responding to methamphetamine i.v. self-administration showed pharmacological agonistic manipulation of the 5-HT1B receptor subtype. |
| Související projekty: |