Do AMPA/kainate antagonists possess potential in the treatment of addiction? Evidence from animal behavioural studies
Název česky | Mají antagonisté AMPA/kainátových receptorů potenciál v léčbě závislosti? Důkazy z behaviorálních studií na zvířatech |
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Autoři | |
Rok publikování | 2025 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY |
Fakulta / Pracoviště MU | |
Citace | |
www | https://www.sciencedirect.com/science/article/pii/S0278584625001095?via%3Dihub |
Doi | http://dx.doi.org/10.1016/j.pnpbp.2025.111355 |
Klíčová slova | Alcohol AMPA/kainate antagonist Amphetamine Cocaine Nicotine Opioids |
Popis | This review examines the potential of AMPA/kainate glutamatergic receptor antagonists in reducing addictive-like behaviours in experimental rodents. To this end, the text summarizes the behavioural results of preclinical studies on stimulant substances (cocaine, amphetamine, methamphetamine, MDMA), nicotine, opioids (morphine and heroin), and alcohol. These experiments employ various protocols and routes of administration, using different strains of mice and rats. |
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