Dynamics of allergy development during the first 5 years of life

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Publikace nespadá pod Ústav výpočetní techniky, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.
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VRBOVÁ Markéta DOROCIAKOVÁ Petra VYŠKOVSKÝ Roman MURINOVA PALKOVICOVA Lubica ČIŽNÁR Peter RAUSOVA Katarina MCNABB Scott J. N. REICHRTOVA Eva BUDINSKÁ Eva THON Vojtěch

Rok publikování 2018
Druh Článek v odborném periodiku
Časopis / Zdroj European journal of pediatrics
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www https://link.springer.com/article/10.1007%2Fs00431-018-3188-9
Doi http://dx.doi.org/10.1007/s00431-018-3188-9
Klíčová slova Allergy; Asthma; Atopic dermatitis; Atopic march; Questionnaire; Rhino conjunctivitis
Popis Allergic diseases have increased in developed countries during the past decades. A cohort of Slovak children was followed from birth to track allergic symptoms dynamics in early childhood. Information on allergic symptoms (atopic dermatitis = AD, rhino conjunctivitis = RC, wheezing = Wh, urticaria = Ur) and food allergies among children was based on clinical evaluation of children by allergists at three developmental stages (infant, toddler, preschool). Out of 320 cases of allergies, 64 infants, 145 toddlers, and 195 preschool children suffered from AD, RC, Wh, Ur, or their combinations (i.e., significant increase with age, p < 0.001). AD first appeared in infants, Wh and/or RC rose mainly in toddlers, and Ur among preschool children. AD in infants or toddlers disappeared in the subsequent developmental stage in approximately one third of all cases. Single AD persistence without remission or extension was not common and accounted only for 6.9% of AD infants' allergic manifestations. In addition to single-symptom allergic diseases, this study also identified several combinations of atopic symptoms. Conclusions: The proportion of multi-symptom allergies increased while single-symptom forms decreased. The observed temporal trends of allergic symptoms correspond to the atopic march.
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