Differences among binding sites of AAL family lectins - High affinity vs. high specificity of sugar binding

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Authors

HOUSER Josef KOMÁREK Jan CIOCI Gianluca IMBERTY Anne WIMMEROVÁ Michaela

Year of publication 2014
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description There are several lectins from opportunistic pathogens in the AAL lectin family. They share the same fold, however they differ in binding site organization and specificity. We combine the functional studies with X-ray crystallography in order to understand the properties of whole lectins as well as their individual binding sites.
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