The asociation of diabetic nephropathy, progression and mortality to functional pentose cycle deficiency as a result of abnormal metabolism od thiamine in DM

Krusová,  Darja; Pácal,  Lukáš; Kaňková,  Kateřina; Tomandl,  Josef; Dvořáková,  Veronika; Olšovský,  Jindřich

The asociation of diabetic nephropathy, progression and mortality to functional pentose cycle deficiency as a result of abnormal metabolism od thiamine in DM

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Authors	KRUSOVÁ Darja PÁCAL Lukáš KAŇKOVÁ Kateřina TOMANDL Josef TANHÄUSEROVÁ Veronika OLŠOVSKÝ Jindřich
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	The results support the role of functional thiamine deficiency in the development of hyperglycaemia- related pathology. Limited intracellular availability of active TKT co-factor seems to be a dominant abnormality.
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