Progrese diabetické nefropatie a role abnormálního metabolizmu thiaminu při funkčním deficitu pentózového cyklu u diabetu

Krusová,  Darja; Pácal,  Lukáš; Kaňková,  Kateřina; Svojanovský,  Jan; Tomandl,  Josef; Olšovský,  Jindřich

Progrese diabetické nefropatie a role abnormálního metabolizmu thiaminu při funkčním deficitu pentózového cyklu u diabetu

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Title in English	Progression of diabetic nephropathy and role of abnormal thiamin metabolism caused by functional deficit of pentose phoshate cycle in diabetes
Authors	KRUSOVÁ Darja PÁCAL Lukáš KAŇKOVÁ Kateřina SVOJANOVSKÝ Jan TOMANDL Josef OLŠOVSKÝ Jindřich
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	The results support the role of functional thiamine deficiency in the development of hyperglycaemia- related pathology. Limited intracellular availability of active TKT co-factor seems to be a dominant abnormality.
Related projects:	Genetic variability of pentose phosphate pathway as a modulating factor of the onset and progression of diabetic nephropathy