125I-labelled iodothyronines: Useful tools for studies of effects of an antidepressant drug fluoxetine in the rat

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Authors	PAVELKA Stanislav
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Chemické Listy
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	Enzyme; radiometric determinations; iodothyronine deiodinases
Description	With the use of adapted radiometric enzyme assays for iodothyronine sulfotransferases and uridine 5’-diphospho-glucuronyltransferase, as well as of our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3, we studied the interaction of an antidepressant drug Fluoxetine with the metabolism of thyroid hormones in the rat.
Related projects:	Proteins in metabolism and interaction of organisms with the environment