Stem cell marker nestin is expressed in plasma cells of patients with monoclonal gammopathies
| Authors | |
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| Year of publication | 2010 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Our results clearly confirmed nestin expression in PCs of MG patients. The percentage of nestin-positive PC and the median fluorescence intensity of expression ranged between patients. Prognostic/predictive significance of these differences requires an evaluation on a larger number of patients and correlation to clinical data. Based on current reports, we hypothesise that nestin could be a prospective marker of myeloma stem cells and a possible target of anti-cancer therapy. Further studies are required to confirm our hypothesis. |
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