Vang-like protein 2 and Rac 1 interact to regulate adherens junctions
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | JOURNAL OF CELL SCIENCE |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | Cell adhesion; Neurulation; PCP; Wnt |
| Description | The Wnt Planar Cell Polarity (PCP) pathway signals through small Rho-like GTPases to regulate the cytoskeleton. Here we investigate the function of the mammalian PCP protein Vangl2. We propose that Vangl2 affects cell adhesion and the cytoskeleton by recruiting Rac1 . |
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