Bilateral elevation of IL-10 protein in both lumbar and cervical dorsal root ganglia following a unilateral nerve ligature

Jančálek,  Radim; Klusáková,  Ilona; Hradilová Svíženská,  Ivana; Dubový,  Petr

Bilateral elevation of IL-10 protein in both lumbar and cervical dorsal root ganglia following a unilateral nerve ligature

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Authors	JANČÁLEK Radim KLUSÁKOVÁ Ilona HRADILOVÁ SVÍŽENSKÁ Ivana DUBOVÝ Petr
Year of publication	2009
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Results of our experiment indicate that the more proximal injury to peripheral nerve the more rapid initial increase and the slower subsequent decrease in level of IL-10 protein within DRG. Moreover, a unilateral nerve ligature induces bilateral elevation of IL-10 protein not only in homonymous lumbar DRG, but also in cervical unaffected ones.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions. Spatio-temporal changes of cytokines in the dorsal root ganglia of experimental neuropathic pain models induced by unilateral nerve injury