Použití jedno-nukleotidových polymorfizmů u analýzy mnohočetného myelomu.

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Title in English	USE OF SINGLE NUCLEOTIDE POLYMORPHISMS IN MULTIPLE
Authors	SLANÝ Michal ŠVÁCHOVÁ Hana HÁJEK Roman
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Klinická onkologie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Oncology and hematology
Keywords	genomics; single nucleotide polymorphisms; signalling pathways; multiple myeloma
Description	Tumor classifi cation and identifi cation of targets for therapeutic applications requires very good knowledge and description of genetic changes connected to an illness. SNP analysis seems to be a valuable tool for detection and characterisation of genetic variations in cancer. The aim of this review is to summarise methods usable for SNP detection and its applicabillity for MM research.
Related projects:	University Research Centre - Czech Myeloma Group From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies