Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear location of nestin

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Authors	LOJA Tomáš CHLAPEK Petr KUGLÍK Petr PEŠÁKOVÁ Martina OLTOVÁ Alexandra CEJPEK Pavel VESELSKÁ Renata
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Oncology Reports
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	nestin; CD133; intermediate filaments; glioblastoma multiforme; cancer stem cells; immunocytochemistry; transmission electron microscopy
Description	A detailed characterization of the established GM7 glioblastoma cell line is given in this paper. This cell line was identified as near-triploid and is characterized by nestin+/CD133+ phenotype with unusual localization of nestin both in cytoplasm and cell nucleus.
Related projects:	Gene Diagnostics and Therapy of Multiform Glioblastoma Molecular basis of cell and tissue regulations Molecular mechanisms of the cell proliferation and differentiation