Methamphetamine behavioural senistization in rodents: interactions with selected drugs and gender.
| Authors | |
|---|---|
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Adiktologie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | methamphetamine; MDMA; morphine |
| Description | Different behavioural rodent models (rat i.v. drug self-administration, mouse agonistic behaviour, open field test,) were used. Behavioural sensitization to metamphetamine was ocnfirmed after repeated pretreatment with methpahetmaine itself but also after MDMA, morphine and cannabinoid CB1 receptor agonist. A higher rewarding effect of methamphetamine was noted in the sensitized animals with estrus-like conditions and attenuated by estrogen deprivation. |
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