A late effect of an anthracycline therapy on 24-hour profile of blood pressure
| Authors | |
|---|---|
| Year of publication | 2008 |
| Type | Article in Proceedings |
| Conference | 5th Conference of the European Study Group on Cardiovascular Oscillations |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | blood pressure; anthracycline; children |
| Description | The aim of the study was nonparametric (differences in each hour, Mann-Whitney test) and parametric evaluation (the least-squares fit of the cosine curve with a period of 24 hours) of the 24-hour recordings of blood pressure (BP) in 45 patients after anticancer therapy with anthracyclines (age groups 13-15, 16-18, 19-22 years), and in 64 age-matched controls. The age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients after anthracycline therapy. This corresponded with a decreased BP in these patients in age between 19-22 years. |
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