Characterization of Haloalkane Dehalogenases DrbA and DmbC: Representatives of Novel Subfamily.

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Title in English	Biochemical Characterization of Haloalkane Dehalogenases DrbA and DmbC: Representatives of Novel Subfamily.
Authors	JESENSKÁ Andrea MONINCOVÁ Marta KOUDELÁKOVÁ Táňa HASAN Khomaini CHALOUPKOVÁ Radka PROKOP Zbyněk GEERLOF Z. DAMBORSKÝ Jiří
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Applied and Environmental Microbilogy
MU Faculty or unit	Faculty of Science
Citation
web	http://loschmidt.chemi.muni.cz/peg/
Field	Biochemistry
Keywords	Isolation; Biochemical Characterization; Haloalkane Dehalogenases; DrbA and DmbC; Subfamily.
Description	This study focuses on two representatives of experimentally uncharacterized haloalkane dehalogenases from the subfamily HLD-III. We report biochemical characterization of the expression products of haloalkane dehalogenases genes drbA from Rhodopirellula baltica SH1 and dmbC from Mycobacterium bovis 5033/66. The DrbA and DmbC enzymes show highly oligomeric structure and very low activity with typical substrates of haloalkane dehalogenases.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)