Brain metabolism and extracellular diffusion parameters after transient global hypoxia and hypoxia/ischemia in the rat

Šlais,  Karel; Homola, Aleš; Zoremba, Norbert; Kuhlen, Ralf; Syková, Eva

Brain metabolism and extracellular diffusion parameters after transient global hypoxia and hypoxia/ischemia in the rat

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Authors	ŠLAIS Karel HOMOLA Aleš ZOREMBA Norbert KUHLEN Ralf SYKOVÁ Eva
Year of publication	2006
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	In this study we investigated changes in the extracellular space parameters (volume fraction and tortuosity), as determined from concentration-time profiles of tetramethylammonium applied by iontophoresis, and the extracellular concentrations of energy-related metabolites (lactate, glucose, pyruvate) and glutamate, monitored by microdialysis, in the rat somatosensory cortex during and after transient hypoxia or hypoxia/ischemia.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.