Extáze, metamfetamin a ligandy kanabinoidních receptorů v modelu agonistického chování myší

Šlais,  Karel; Landa,  Leoš; Šulcová,  Alexandra

Extáze, metamfetamin a ligandy kanabinoidních receptorů v modelu agonistického chování myší

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Title in English	Ecstasy, methamphetamine and cannabinoid receptor ligands in the model of agonistic behaviour in mice
Authors	ŠLAIS Karel LANDA Leoš ŠULCOVÁ Alexandra
Year of publication	2006
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Repeated administration of methamphetamine or ecstasy led to sensitization to antiaggressive methamphetamine effects. Repeated pre-treatment with CB1 receptor agonist induced cross-sensitization to methamphetamine challenge dose and in contrary repeated application of CB1 receptor antagonist with methamphetamine suppressed the sensitization phenomenon.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.