Nestin expression in cell lines derived from high-grade astrocytomas.
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Proceedings |
| Conference | International Journal of Mol. Medicine 14 (Sup. 1) - the 9th World Congress on Advances in Oncology and the 7th International Symposium on Molecular Medicine |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | nestin; intermediate filaments; immunocytochemical and cytogenetic analysis; astrocytomas |
| Description | Two cell lines were established from biopsy samples of patients surgically treated for glioblastoma multiforme. Genetic abnormalities were studied on fresh bioptic material using interphase fluorescence in situ hybridization (iFISH); cultivated cell lines were analyzed by G-banding and spectral karyotyping (SKY). The expression of intermediate filament proteins (vimentin, GFAP, nestin) was analyzed at different passages for both cell lines. |
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