Two MMP-2 Promoter Polymorphisms (-790T/G and -735C/T) in Chronic Heart Failure

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Authors	VAŠKŮ Anna GOLDBERGOVÁ Monika IZAKOVIČOVÁ HOLLÁ Lydie ŠPINAROVÁ Lenka ŠPINAR Jindřich VÍTOVEC Jiří VÁCHA Jiří
Year of publication	2003
Type	Article in Periodical
Magazine / Source	Clin Chem Lab Med
MU Faculty or unit	Faculty of Medicine
Citation
Field	Cardiovascular diseases incl. cardiosurgery
Keywords	Chronic heart failure; gene polymorphism; MMP-2; total cholesterol
Description	The heterozygote CT of -735C/T MMP-2 polymorphism exhibits a 7 times higher odds ratio for the patients with chronic heart failure with lower levels of total cholesterol, especially for non-hypertensive men with chronic heart failure.
Related projects:	Molecular pathophysiology of multigene diseases