Structures of the lectins from Pseudomonas aeruginosa: Insights into molecular basis for host glycan recognition

Warning

This publication doesn't include Institute of Computer Science. It includes Faculty of Science. Official publication website can be found on muni.cz.

Authors	IMBERTY Anne WIMMEROVÁ Michaela MITCHELL Edward P. GILBOA-GARBER Nechama
Year of publication	2004
Type	Article in Periodical
Magazine / Source	Microbes and Infection
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	lectin; Pseudomonas aeruginosa; cystic fibrosis; crystal structure
Description	The opportunistic human pathogen Pseudomonas aeruginosa produces two lectins in close association with virulence factors: PA-IL and PA-IIL, which bind to galactose- and fucose/mannose-containing glycoconjugates, respectively. We review here the structural aspects of these lectins are related to their putative roles in host recognition, cell surface adhesion and biofilm formation.
Related projects:	Biomolecular Center