Determination of 5-methyl-2'-deoxycytidine 5'-monophosphate and 2'-deoxycytidine 5'-monophosphate in the cell homogenate using HPLC

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Authors	HAVLIŠ Jan DOHNAL Vlastimil REVILLA VÁZQUEZ Alma Luísa KOZÁK Libor HAVEL Josef
Year of publication	1999
Type	R&D Presentation
MU Faculty or unit	Faculty of Science
Citation
Description	MALDI-TOF MS is a suitable method for extremely fast semi-quantitative determination of purines and pyrimidines in urine. MVA (multivariate approach), represented by experimental design combined with ANN, is a more correct approach to optimization of the separation conditions than that of classical SVA (single variation method) and enables faster optimization of the method with lower number of experiments.
Related projects:	Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles