One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate

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Authors	MOHAMED Walid Fathalla ČAJAN Michal PAZDERA Pavel MAREK Jaromír
Year of publication	2001
Type	Article in Periodical
Magazine / Source	Molecules
MU Faculty or unit	Faculty of Science
Citation
Field	Organic chemistry
Keywords	N-(2-cyanophenyl)benzimidoyl isothicyanate; quinazolines; thioureas
Description	1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate with secondary amines. The products underwent trans-amination reactions. Products were identified by FTIR, 1 H-NMR, 13 C NMR, mass spectroscopy and X-ray crystallography.
Related projects:	Chalcogen organic compounds - synthesis, transformation and structure elucidation