NMR methodology for the study of nucleic acids
| Authors | |
|---|---|
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Current Opinion in Structural Biology |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | NMR; nucleic acids; NMR methods; review |
| Description | During the past few years, NMR methodology for the studey of nucleic acids has benefited from new developments that greatly improved state-of-the-art technology for the precise determination of three-dimensional structures. Substantial progress has been made in designing experimental protocols for the measurement of residual dipolar couplings, in sensitivity optimization for triple-resonance experiments and in detection of hydrogen bonds in developing computational methods for structure refinement using NMR restraints. |
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