Establishment of reference ranges for ClotPro® in parturients

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Authors	VRBICA Kamil HRDÝ Ondřej ŠTINGL Jan HRUBAN Lukáš GÁL Roman
Year of publication	2025
Type	Article in Periodical
Magazine / Source	ANAESTHESIA
MU Faculty or unit	Faculty of Medicine
Citation
web	https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.16776
Doi	https://doi.org/10.1111/anae.16776
Description	Severe haemorrhage remains the leading cause of maternal mortality worldwide. International guidelines recommend the use of viscoelastic testing to guide post-partum haemorrhage (PPH) treatment. Unlike traditional assays, viscoelastic testing uses whole blood and provides real-time clotting data, enabling faster decisions. Viscoelastic testing results correlate with fibrinogen levels and help predict PPH progression and outcomes. Previous studies used older devices like ROTEM® (Werfen, Barcelona, Spain) or TEG® (Haemonetics Corporation, Boston, MA, USA) but not the newer ClotPro® (Haemonetics Corporation). This shares key features with ROTEM yet may yield different results; thus, ClotPro-specific reference ranges are needed. This study aimed to establish corresponding reference ranges in parturients using the ClotPro device.
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