Probabilistic Modelling and Decision Support in Personalized Medicine

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Authors

JAVORNÍK Michal DOSTÁL Otto ROČEK Aleš

Year of publication 2023
Type Chapter of a book
MU Faculty or unit

Institute of Computer Science

Citation
Description The concept of personalized medicine, often called the biggest revolution in medicine, is becoming an emerging practice. The article presents personalized medicine in a broader context as an interdisciplinary issue covering the current trends of information and communication technology in medicine, legal aspects, and probabilistic network modelling. Employing the concept of probabilistic network reasoning means extracting the meaningful knowledge, mathematizing it, incorporating the particular patient information and then using inference mechanisms of the created mathematical model for personalized decision support. Bayesian networks can serve as a multidimensional decision support framework representing the real-world medical domain. Their power, together with the possibilities of global sharing of necessary medical knowledge, represents a promising approach of extracting new, often hidden, knowledge about the given medical domain and thus opens up new ways of achieving the delivery of personalized medicine. Establishing patient diagnosis and treatment prognoses are the critical issues in personalized decision support. Mathematical modelling is beginning to play an irreplaceable role here.
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