Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.

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Authors

REIGL Tomáš NAVRKALOVÁ Veronika PORC Jakub Paweł PÁL Karol STRÁNSKÁ Kamila POSPÍŠILOVÁ Šárka PLEVOVÁ Karla

Year of publication 2023
Type Conference abstract
MU Faculty or unit

Central European Institute of Technology

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Description High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research', he has been involved in the development of several software projects, e.g.: LYNX (LYmphoid NeXt-Generation Sequencing) analytical software, CLLue, ARResT/Interrogate, ARResT/Subsets aka Encyclopedia of CLL Subsets. LYNX is a tailor-made bioinformatic tool for a new custom-designed capture-based NGS panel. With this tool, a user can analyze molecular markers, such as gene mutations, copy number variations, antigen receptor rearrangements, and translocations in the most common lymphoid malignancies. CLLue is an interactive web-based tool that allows users to perform a visual exploratory data analysis, identification of important and significant features in given groups based on statistical tests, and de novo clustering on their data.
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