xMAP Technology: Applications in Detection of Pathogens

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Authors

RESLOVÁ Nikol MICHNÁ Veronika KAŠNÝ Martin MIKEL Pavel KRÁLÍK Petr

Year of publication 2017
Type Article in Periodical
Magazine / Source Frontiers in Microbiology
MU Faculty or unit

Faculty of Science

Citation
Doi http://dx.doi.org/10.3389/fmicb.2017.00055
Field Genetics and molecular biology
Keywords xMAP; magnetic microspheres; multiplex detection; nucleic acid detection; immunoassay; pathogen identification; diagnostics
Attached files
Description xMAP technology is applicable for high-throughput, multiplex and simultaneous detection of different analytes within a single complex sample. xMAP multiplex assays are currently available in various nucleic acid and immunoassay formats, enabling simultaneous detection and typing of pathogenic viruses, bacteria, parasites and fungi and also antigen or antibody interception. As an open architecture platform, the xMAP technology is beneficial to end users and therefore it is used in various pharmaceutical, clinical and research laboratories. The main aim of this review is to summarize the latest findings and applications in the field of pathogen detection using microsphere-based multiplex assays.
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