Towards functional repertoire of the earliest proteins

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Authors

SOBOLEVSKY Y. GUIMARAES R. C TRIFONOV Eduard Nikolajevič

Year of publication 2013
Type Article in Periodical
Magazine / Source Journal of Biomolecular Structure & Dynamics
MU Faculty or unit

Central European Institute of Technology

Citation
Doi http://dx.doi.org/10.1080/07391102.2012.735623
Field Genetics and molecular biology
Keywords ABC cassettes; protein modules; earliest proteins; omnipresent motifs; last universal cellular ancestor
Description The conserved protein sequence motifs present in all prokaryotic proteomes, omnipresent motifs, presumably, correspond to the earliest proteins of the Last Universal Cellular Ancestor, from which all the proteomes have descended. Future analysis of less conserved sequence motifs may reveal at what degree of conservation (stage of evolution) the metabolic enzymes could have entered the scene.
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