MALDI MS and SALD ICP MS: Complementary Detection Techniques for Metalloproteomics

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Authors	TOMALOVÁ Iva FOLTYNOVÁ Pavla KANICKÝ Viktor PREISLER Jan
Year of publication	2013
Type	Article in Proceedings
Conference	CECE Junior 2013
MU Faculty or unit	Central European Institute of Technology
Citation
Field	Analytic chemistry
Keywords	metalloproteomics; SALD ICP MS; MALDI MS
Description	Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) and substrate-assisted laser desorption inductively coupled plasma (SALD ICP) MS are proposed as complementary detection techniques that allows acquisition of both molecular and element specific information from a single capillary electrophoresis (CE) run recorded on a custom-designed sample target. The whole concept is demonstrated on the analysis of rabbit-liver metallothionein (MT) isoform mixture.
Related projects:	CEITEC - Central European Institute of Technology Nové strategie úpravy vzorků pro desorpční hmotnostní spektrometrii