Motion Artefact in Voltage-Sensitive Fluorescent Dye Emission During Repeated Ischemia of Isolated Heart

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Authors	JANOUSEK O. KOLAROVA J. RONZHINA M. NOVÁKOVÁ Marie PROVAZNIK I.
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Physiological Research
MU Faculty or unit	Faculty of Medicine
Citation
Field	Physiology
Keywords	Motion artefact; Ischemia; Isolated rabbit heart; Voltage-sensitive dye
Attached files	Motion_Artefact_neni_ev_list.pdf
Description	Motion artefact (MA) in voltage-sensitive fluorescent signals causes significant debasement of action potential. During ischemia and reperfusion in isolated rabbit heart, this artefact develops in a manner which may be described by the time of its onset, level, and shape. The MA during ischemia: (a) may become substantial with approximately two minutes delay after establishing global ischemia; (b) may be almost twice as high as the physiological action potential and decreases both with time and repetition of ischemia.
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