Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
1999
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Effects of propiverine and its major metabolites on drug metabolising enzymes in rat and human
Sborník abstrakt - MEFA kongres, year: 1999
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Effects of various serotonin agonists, antagonists, and uptake inhibitors on the discriminative stimulus effects of methamphetamine in rats
The Journal of Pharmacology and Exper. Therapeutics, year: 1999, volume: 291, edition: 1
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Farmakologie hypnotik
Sborník abstrakt - 1. sjezd o spánku a 5. pražské sympozium o spánkové apnoi, year: 1999
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Fluoxetin modifikuje "self-administration" morfinu u potkanů
41. Česko-Slovenská psychofarmakologická konference, year: 1999
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Fluoxetine influence on methamphetamine i. v. self-administration in rats
EBPS 1999, Abstracts, year: 1999
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Fluoxetine modifies morphine self-administration in rats
Homeostasis, year: 1999, volume: 39, edition: 3-4
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Gross Anatomy and Structure of the Human Nervous System - Part I. Surface Anatomy and Structural Arrangement of the Central Nervous System
Year: 1999, edition: Vyd. 1, number of pages: 138 s.
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Changes of CYP2D1/6 activity evoked by long-term medication with substrate psychotropics in rats
Homeostasis, year: 1999, volume: 1999, edition: 39
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Ictal activity Recorded in the Basal Ganglia. A video-EEG Study. Abstracts
Abstracts from the 23 rd International Epilepsy Congress., year: 1999
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Immunohistochemical localization of laminin-1 in the acellular nerve grafts is associated with migrating Schwann cells which display corresponding integrin receptors
The Histochemical Journal, year: 1999, volume: 31, edition: 2