High-affinity lectins from pathogens: the potential targets for antiadhesive drug design

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Authors	ŠULÁK Ondřej MALINOVSKÁ Lenka CIOCI Gianluca HOUSER Josef KOSTLÁNOVÁ Nikola LAMEIGNERE Emilie POKORNÁ Martina IMBERTY Anne WIMMEROVÁ Michaela
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Materials Structure in Chemistry, Biology, Physics and Technology
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	lectin; antiadhesive therapy
Description	Protein-carbohydrate interactions play an important role in many biologically relevant processes. The contribution is focused on lectins from human opportunistic pathogens, which display sub-micromolar range affinity towards their carbohydrate ligands.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Biomolecular centre Design of Carbohydrates and Glycomimetics as Antibacterial and Antiviral Drugs