Structural Covariance of Early Visual Cortex Is Negatively Associated With Posttraumatic Stress Disorder Symptoms: A Mega-Analysis From the ENIGMA PTSD Working Group
| Authors | |
|---|---|
| Year of publication | 2026 |
| Type | Peer-reviewed scientific article |
| Magazine / Source | Biological Psychiatry: Cognitive Neuroscience and Neuroimaging |
| MU Faculty or unit | |
| Citation | |
| web | https://www.sciencedirect.com/science/article/pii/S2451902225002216?via%3Dihub |
| Doi | https://doi.org/10.1016/j.bpsc.2025.07.005 |
| Keywords | early visual cortex; structural covariance; posttraumatic stress disorder; ENIGMA PTSD; neuroimaging mega-analysis |
| Description | BACKGROUND: Identifying robust neural signatures of posttraumatic stress disorder (PTSD) symptoms is important to facilitate precision psychiatry and help in understanding and treatment of the disorder. Emergent research suggests that the structural covariance of early visual regions is associated with later PTSD development. However, large-scale analyses are needed in heterogeneous samples of trauma-exposed and trauma-naive individuals to determine whether such a neural signature is a robust marker of vulnerability. |
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